Aiming at the problems of limited monitoring area and difficult target locating in video security surveillance system, a radar-guided video linkage monitoring model was established with the characteristics of wide radar monitoring range and freedom from optical conditions. On this basis, a target location algorithm and a multi-target selection algorithmm were proposed. Firstly, according to the target information detected by radar, the corresponding camera azimuth and pitch angle of a moving target in the system linkage model were automatically calculated so that the target could be accurately locked, monitored and tracked by camera in real-time. Then, with multiple targets appearing in the surveillance scene, the multi-target selecting algorithm was used for data weighted fusion of discrete degree of target, radial velocity of target and the distance between target and camera to select the target with the highest priority for intensive monitoring. The experimental results show that, the locating accuracy of the proposed target location algorithm for pedestrians and vehicles can reach 0.94 and 0.84 respectively, which can achieve accurate target location. Moreover, the proposed multi-target selection algorithm can effectively select the best monitoring target in complex environment, and has good robustness and real-time performance.